Source: http://news.feedzilla.com/en_us/stories/politics/top-stories/252166053?client_source=feed&format=rss
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Sunday, September 30, 2012
New pathogen epidemic identified in sub-Saharan Africa
ScienceDaily (Sep. 27, 2012) ? Researchers have found that the spread of a dangerous bacteria that can be fatal in up to 45% of people infected in sub-Sahara Africa may have been instigated by the emergence and spread of HIV in Africa. The study also found that one of the major contributing factors for the successful spread of the disease -- non-Typhoidal Salmonella (iNTS) -- was the acquisition of genes that afford resistance to several front line drugs used to treat blood-borne infection such as iNTS.
A new study out September 30 reveals that the emergence and spread of a rapidly evolving invasive intestinal disease, that has a significant mortality rate (up to 45%) in infected people in sub-Saharan Africa, seems to have been potentiated by the HIV epidemic in Africa.
The team found that invasive non-Typhoidal Salmonella (iNTS) disease is caused by a new form of the bacteria Salmonella Typhimurium that has spread from two different focal hubs in Southern and Central Africa beginning 52 and 35 years ago, respectively. They also found that one of the major contributing factors for the successful spread of iNTS was the acquisition of genes that afford resistance to several front line drugs used to treat blood-borne infection such as iNTS.
iNTS is a blood-borne infection that kills approximately one of four people in sub-Saharan Africa who catch it. Yet, in the rest of the world, NTS is a leading cause of acute inflammatory diarrhea that is self-limiting and tends to be fatal in less than 1 per cent of people infected. The disease is more severe in sub-Saharan Africa than the rest of the world because of factors such as malnutrition, co-infection with malaria or HIV and potentially the novel genotype of the Salmonella bacteria.
"The immune system susceptibility provided by HIV, malaria and malnutrition at a young age, may provide a population in sub-Saharan Africa that is large enough for this detrimental pathogen to enter, adapt, circulate and thrive," says Chinyere Okoro, joint first author from the Wellcome Trust Sanger Institute. "We used whole genome sequencing to define a novel lineage of Salmonella Typhimurium that is causing a previously unrecognised epidemic across the region. Its genetic makeup is evolving into a more typhoid like bacteria, able to efficiently spread around the human body"
From sequenced samples, the team created a phylogenetic or 'family tree', depicting the pathogen's evolution, dating when each sample first emerged and overlaying this with geographical information about where these samples came from. They found that this invasive disease comprises of two very closely related waves; the first wave originated from a possible south-eastern hub, about 52 years ago and the second originated about 35 years ago, possibly from the Congo Basin.
"The HIV epidemic in sub-Saharan Africa is thought to have begun in a central region and underwent expansion eastwards, a strikingly similar dynamic to that observed for second iNTS wave," says Dr Robert Kingsley, joint first author from the Wellcome Trust Sanger Institute. "Our findings suggest the current epidemic of iNTS and its transmission across sub-Saharan Africa may have been potentiated by an increase in the critical population of susceptible, immune-compromised people."
The team identified that the vast majority of samples from the second wave of iNTS contains a gene that makes them resistant to chloramphenicol, a frontline antibiotic in the treatment of Salmonella. This gene was not present in the samples from the first wave of iNTS. This observation suggests that iNTS acquired this gene early on in the evolution of the second wave, probably around the time of its spread from the Congo basin.
"Because it acquired resistance to chloramphenicol, this pathogen has much greater opportunity to survive and spread across the region," says Professor Gordon Dougan, lead author from the Wellcome Trust Sanger Institute. "This is the first time that the power of whole-genome sequencing has been used to track the spread of iNTS. Our research highlights the power this approach has to monitor the emergence and spread of dangerous pathogens both locally and globally over time."
"There has been some evidence that this disease can be passed from human to human. Now the race is on to discover how NTS is actually transmitted in sub-Saharan Africa so that effective intervention strategies can be implemented."
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Story Source:
The above story is reprinted from materials provided by Wellcome Trust Sanger Institute.
Note: Materials may be edited for content and length. For further information, please contact the source cited above.
Journal Reference:
- Chinyere K Okoro, Robert A Kingsley, Thomas R Connor, Simon R Harris, Christopher M Parry, Manar N Al-Mashhadani, Samuel Kariuki, Chisomo L Msefula, Melita A Gordon, Elizabeth de Pinna, John Wain, Robert S Heyderman, Stephen Obaro, Pedro L Alonso, Inacio Mandomando, Calman A MacLennan, Milagritos D Tapia, Myron M Levine, Sharon M Tennant, Julian Parkhill, Gordon Dougan. Intracontinental spread of human invasive Salmonella Typhimurium pathovariants in sub-Saharan Africa. Nature Genetics, 2012; DOI: 10.1038/ng.2423
Note: If no author is given, the source is cited instead.
Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of ScienceDaily or its staff.
Source: http://feeds.sciencedaily.com/~r/sciencedaily/~3/SuSCC8XrBPo/120930141545.htm
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Worx SD Power Screwdriver ? I am the Law
One of the biggest pains with using drills and power screwdrivers is having to change bits all the time, however Worx has come up with a neat solution. ?The Worx SD Power screwdriver is powered by a 4V Li-Ion battery and comes with a handy LED work light. ?It’s big selling point is the six [...]
Source: http://the-gadgeteer.com/2012/09/29/worx-sd-power-screwdriver-i-am-the-law/
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Saturday, September 29, 2012
Choosing A Sink Vanity Cabinet | Home improvement knowledge
Are you fixing your house? Fixing your bathroom perhaps? Are you thinking about those little things to make the space more of a home than a house, showcasing your personal taste? Bathrooms are one of those overlooked rooms that we sometimes look at as merely practical, but it is actually one of those areas that we spend a significant amount of our time in. It?s the first place we go to when we wake up and the last place we visit before going to bed, it is as much a personal space where we seek a few moments of solitude and respite. Therefore we must also take a care in fixing or designing one of the smallest rooms in a house or apartment that we call home.
What do we want inside our bathrooms? Aside from the usual bath or shower, toilet and mirror, sinks and cabinets, what else could we possibly add? Bathrooms can look more elegant when a sink vanity cabinet is present. There are many different types of sink corner cabinets. So you have to consider for example the type of wood you?d like. Do you like dark cherry wood, or do you go for the lighter pine wood or maybe you would like to settle for something in between? After deciding what type of wood you like, now you decide how big it would be. This basically depends on the space of your bathroom: too big a vanity cabinet would cramp the space and eliminate even the need for the sink vanity cabinet to begin with. Having a small sink vanity cabinet would severely limit the things you could put in your cabinet, and it would be merely an accessory rather than something useful.
There are many choices of sink vanity cabinets and sink corner cabinets as well, from the traditional single sink vanity cabinet, the double sink vanity cabinet, to the modern sink vanity cabinet. The traditional sink vanity cabinet, as the name suggests, has a single sink with a cabinet underneath. If one is looking for elegance and old world touch then you could go for this kind of vanity.
The double sink vanity has two sinks and is for those who have the floor space to accommodate this kind of sink. This type is actually the best possible choice. Imagine having two sinks and being able to simultaneously use them with your family or partner. For those who would prefer a more current look, then they should go for the modern vanity sink cabinets. You will also need to decide what type of sink you?d like, a glass one perhaps, the marble kind or the aluminum one.
Sink vanity cabinets are accessories in more ways than being simply a piece of furniture that looks good. They can also make the drains or pipes connecting to the sink hidden from view. The sink vanity cabinet has the amenities of a sink but the convenience of a cabinet. The use of space is not only aesthetic but practical as well.
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Source: http://www.gradcmu.net/choosing-a-sink-vanity-cabinet
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Casio XJ-H2650
The Casio XJ-H2650 isn't Casio's brightest projector, but it's part of Casio's Pro Series, which is its brightest line of projectors. It also offers WXGA (1280 by 800) native resolution, the highest in the Pro Series line. That's a moderately big deal, because until now, if you wanted a WXGA Casio projector you had to settle for one of the lower brightness models. The XJ-H2650 delivers the highest brightness Casio offers with WXGA resolution, and the highest resolution with Pro Series brightness, all of which makes it a good choice for mid-size conference rooms and classrooms.
Casio rates the XJ-H2650 at 3500 lumens, a bit less bright than the 4,000 lumen Casio XJ-H1750 Pro Series that I reviewed earlier this year. However, the XJ-H1750 offers a native XGA (1,024 by 768) resolution.
The only other Pro Series model with WXGA resolution is the XJ-H2650's near twin, the Casio XJ-H2600 ($2,000 street). Casio says that the two models are identical except for the addition of USB A, USB B, and LAN ports to the XJ-H2650, along with features that depend on those ports. Most notably, the XJ-H2650's USB A port lets you plug in a supplied Wi-Fi adaptor so you can connect directly with, and send data images from, Windows and Mac computers as well as most Android, iOS, and Windows smartphones and tablets.
The extra ports also let you plug in a memory key to read JPG and a few other file formats directly, control the projector over a network, send data images over a network, and add interactivity with an interactive pen and software option ($260 street). However, the interactive feature is hard to recommend, since the projector's standard-throw lens would make it hard to interact with the image without casting shadows that would get in the way. All other features on the XJ-H2600 and XJ-H2650 should be identical, so the rest of the comments in this review should apply to both.
Basics, Setup, and Connections
Like all current Casio projectors, the XJ-H2650 is built around Casio's hybrid light source, consisting of LEDs and a laser paired with a DLP chip. The LEDs produce the red and blue primaries directly. The laser shines on a phosphor element to produce green.
Not too surprisingly, given that both projectors are part of the same Pro Series, the XJ-H2650 shares a lot of its basic features with the XJ-H1750. In particular, it weighs almost the same, at 15.6 pounds, which makes it most appropriate for permanent installation or room to room portability on a cart.
Setup is standard, with a manual focus and a manual 1.2x zoom, which gives you some welcome flexibility in how far you can put the projector from the screen for a given size image. In addition to the LAN and USB ports I've already mentioned, connection choices include the usual HDMI for a computer or video source, VGA for computer or component video, and both S-video and composite video inputs.
Brightness and Eco Modes
In my tests, the XJ-H2650 was easily bright enough in its brightest mode for a 78-inch wide (92-inch diagonal) image to stand up to the typical level of ambient light in an office or classroom setting. Even better, it was bright enough at that size so you could easily take advantage of its eco modes to minimize power use and save on electricity.
Most projectors offer one bright mode and one eco mode that lets you lower brightness and power consumption. Beyond that, they offer color presets that can also affect brightness, but are, in theory, meant to adjust color.
The XJ-H2650 gives you more flexibility for brightness and power use, with two non-eco modes, which I measured at 340 watts and 290 watts, plus five eco modes, with a measured range of 260 to 115 watts. With multiple eco modes, you have the freedom to pick the best color setting first, and then choose the least bright mode with the brightness you need, instead of using the color presets to adjust brightness. Also worth mention is that the only projector I've seen with more eco-mode levels is the laser-based BenQ LX60ST that I recently reviewed.
Source: http://feedproxy.google.com/~r/ziffdavis/pcmag/~3/rIXB7qr2W0A/0,2817,2410265,00.asp
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MRSA research identifies new class of anti-bacterial drugs, shows how 'superbug' DNA may help scientists predict transmission routes
ScienceDaily (Sep. 28, 2012) ? Researchers at The Ohio State University have discovered a new class of treatment against methicillin-resistant Staphylococcus aureus (MRSA) as well as evidence of a growing need to quickly genotype individual strains of the organism most commonly referred to as the "superbug."
The two separate studies were funded by the Ohio State Center for Clinical and Translational Science (CCTS) with a goal of increasing the MRSA knowledge-base from both a basic science "bench" perspective, as well as using real-time data from infected communities to determine how MRSA spreads.
"The public is most familiar with the dramatic progression of skin infections caused by MRSA, but MRSA is responsible for a range of difficult to treat illnesses," noted Dr. Kurt B. Stevenson, professor of Infectious Diseases at the Ohio State College of Medicine, and primary investigator of the CCTS-funded study following the transmission of MRSA infections in communities. "While we've seen a decrease in the number of MRSA cases, identifying new agents and tracking methods will be critical to stopping these infections before they can start."
Cancer treatment search leads to potential MRSA killer, immune booster
In 2002, Ching Shih Chen, professor of medicinal chemistry at Ohio State College of Pharmacy, and a team of researchers were creating a library of anti-cancer agents built around the scaffold of the molecules of celecoxib, a popular arthritis treatment in a family of drugs known as cyclooxygenase-2 (COX-2) inhibitors. This effort yielded OSU-03012 (AR12), a compound that is currently in a Phase I clinical trial as anticancer agent at the OSU Comprehensive Cancer Center -- Arthur G. James Cancer Hospital and Richard J. Solove Research Institute.
After observing how the substance acted within breast cancer cells, Hao-Chieh Chiu, a then postdoctoral researcher in Chen's lab, realized that the derivatives were suppressing a mechanism that bacteria also use to take over their host cells. Chiu decided, with the support of Dr. Chen, to focus his research on testing the COX-2 compound library against a variety of bacteria.
"When the compounds showed anti-bacterial activity against Salmonella and Francisella, we began testing efficacy against a variety of pathogenic bacteria, including Staphylococcus aureus, Enterococcus, and Streptococcus," said Chiu, who is an assistant professor at the Department of Clinical Laboratory Sciences and Medical Biotechnology at National Taiwan University. "It became clear that these celecoxib analogues had a unique anti-bacterial activity, and they appeared to be most potent against Staph aureus and other MRSA strains."
The researchers narrowed the library down to a single agent (dubbed "compound 46") and moved to testing in MRSA-infected mice. Published in the August issue of Bioorganic and Medicinal Chemistry, the authors report that an intraperitoneal administration of compound 46 resulted in increased survival in MRSA-infected mice versus untreated mice. "It was particularly gratifying to see that these compounds, originally designed as anticancer agents, work as a novel class of anti-bacterial agents based on the same principle in bacterial cells," said Chen.
The researchers are hopeful that this early work will ultimately provide insights on the development of a treatment for antibiotic resistant infectious diseases. The team is already working with scientists at the Ohio State Center for Microbial Interface Biology, led by Dr. Larry Schlesinger, to use this technology to develop novel agents against tuberculosis, another public health threat facing similar issues with drug resistance.
MRSA DNA tells scientists where it's been -- and where it might go next
Investigators in the Division of Infectious Diseases at The Ohio State College of Medicine and Wexner Medical Center have created a statewide "roadmap" of MRSA infections that is helping them better predict how -- and where -- MRSA will spread.
The team, funded by the Centers for Disease Control and Prevention (CDC), used diverse methods from geographic analysis to molecular genotyping to track more than 1,000 MRSA cases from the Wexner Medical Center and community hospitals across Ohio. Experts say using a variety of tracking methods is essential to stopping infections before they start.
"With data from different sources, we've markedly improved our understanding of how MRSA is acquired and then spread among healthcare facilities. For example, we identified a very rare strain in the US, ST-239, which originated in Asia, spread to hospitals in Western Europe, and was introduced to Ohio sometime in the past two decades. It's that level of knowledge that will help us change the course of transmission," said Stevenson, whose research on ST-239 and its presence in healthcare facilities was published online ahead of print in the October issue of Emergent Infectious Diseases.
Using funding from the CCTS, investigators further applied diverse tracking methods to bloodstream isolates from hospitals in Franklin County, Ohio, as well as skin and soft tissue infections among patients receiving primary care in a variety of settings. The results not only demonstrated the value of rapid molecular typing in examining the distribution and transmission of individual MRSA strains, but showed that particular strains tended to cluster in specific places.
"These studies have demonstrated that specific molecular types of MRSA are linked to specific types of infections, or even specific settings. For instance, there are strains that tend to colonize catheters, strains that are more commonly found in nursing homes," said Shu-hua Wang, assistant professor of Infectious Diseases, who worked with Stevenson as part of a mentorship grant from the CCTS. "As we understand why certain MRSA strains behave as they do, more targeted interventions for prevention and treatment can be tested."
Stevenson is hopeful that technology will someday provide a quick and inexpensive on-site genomic analysis of MRSA. In anticipation of that day, the team is using the "roadmap" data to create a MRSA molecular library that provides a detailed background on individual strains, including its drug resistance, weaknesses, and most likely source of transmission. "We're envisioning a future where every patient admitted into a hospital will get a rapid, strain-specific MRSA test and within minutes, a doctor will know exactly what protocol to follow to stop the patient from getting sick, and stop the bacteria from spreading," said Stevenson.
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Story Source:
The above story is reprinted from materials provided by Ohio State University Center for Clinical and Translational Science, via Newswise.
Note: Materials may be edited for content and length. For further information, please contact the source cited above.
Journal Reference:
- Shu-Hua Wang, Yosef Khan, Lisa Hines, Jos? R. Mediavilla, Liangfen Zhang, Liang Chen, Armando Hoet, Tammy Bannerman, Preeti Pancholi, D. Ashley Robinson, Barry N. Kreiswirth, Kurt B. Stevenson. Methicillin-ResistantStaphylococcus aureusSequence Type 239-III, Ohio, USA, 2007?20091. Emerging Infectious Diseases, 2012; 18 (10): 1557 DOI: 10.3201/eid1810.120468
Note: If no author is given, the source is cited instead.
Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of ScienceDaily or its staff.
Source: http://feeds.sciencedaily.com/~r/sciencedaily/top_news/top_health/~3/iCS0aTGXf70/120928125105.htm
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6 Q's About the News | Don't Eat the Snow - NYTimes.com
6 Q?s About the News
Use the photo and related articles to answer basic news questions.
WHAT does the Arizona Snowbowl plan to use this year to make artificial snow?
WHERE is the ski resort located?
WHO owns the land?
WHO is protesting the ski resort?s plans?
HOW might the ski resort?s plans affect human health, according to Taylor McKinnon?
HOW might the ski resort?s plans affect the environment?
HOW much money might the local economy receive if the plans go into effect?
WHY is it necessary for ski resorts to make artificial snow?
WHY are Indians protesting the ski resort?s plans?
WHEN will the ski resort?s plan go into effect?
WHEN did Klee Benally start protesting?
WHEN does Mr. Benally plan to stop protesting?
WHEN has there been a debate in your area over environmental issues?
Related: Our lesson plans on the environment and society, including ?Environment, Society and Economy: Exploring Sustainability.?
Source: http://learning.blogs.nytimes.com/2012/09/28/dont-eat-the-snow/
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Thursday, September 27, 2012
Air Max Jordan 13 White Black Red | ArticleBro.com
Banner advertisements are the foundation of online advertising. They helped accompany online commercial to the akin it is at today. It was banderole ads that were the aboriginal aloft anatomy of advertisements acclimated to bazaar on the internet and today they are still one if not the top anatomy of online advertising.
Banner ads are the internet?s anatomy of advance advertisements. The advantages that banners accept over billboards assume countless. They can use technology to ambition specific users in their ambition bazaar and even to almanac and assay abstracts and statistics of the bags of users who are examination their ads.
There are so abounding agency that a administrator or website buyer can pay for their banderole advertisements. The a lot of accepted anatomy of paying for any affectionate of online advertisement is a pay per bang method. This adjustment can be acclimated both with and after banderole ads and should be advised by all online advertisers.
Why should I acquaint online?
Before because how to pay for your advertisements, you should apperceive why commercial online can account you. There are abounding things that online advertisements can do for your business. Air Max Jordan 6 White Black Blue
Increase acquaintance and acknowledgment of your company
Bring added targeted, superior cartage to your website
Create added leads and sales for your site Air Jordan 3 Retro White True Blue Shoes
The aloft allowances of online commercial are just three of the capital allowances of application online advertising. There are abounding abate allowances that are advantageous but not as important as the ones listed above. Depending on how important anniversary one of those three things is for you alone can advice actuate how you should acquaint on the internet and how you should pay for your advertisements.
Terms and Concepts Commonly Associated with Online Commercial and Marketing
There are abounding key agreement and concepts that are acclimated if anecdotic online commercial and online business on a circadian basis. Before in fact administering any commercial on the internet, you should accept at the actual atomic a basal compassionate on these agreement and what they mean.
Advertisements Accomplish Impressions
An consequence occurs every individual time that an advertisement is viewed. If a webpage endless that contains an advertisement, usually a banderole ad, an consequence is said to action because the advertisement appeared to the website visitor. Impressions are one way to admeasurement how about an ad is accepting apparent and can be acclimated to actuate how to pay for ads.
Cost Per Mille or Bulk Per Impression Air Max Jordan 11 Silvery Grey
Cost per mille and bulk per impressions are appropriately acclimated to accurate bulk per one-thousand impressions. This agency that a administrator will pay to accept their ad displayed per every one-thousand times it is apparent by viewers. For example, an advertiser may pay fifteen dollars to accept their ad displayed one-thousand times. This agency that they are spending one and a bisected cents for every eyewitness that sees their ad.
Click-Through
A click-through occurs if a website aggregation clicks on an ad and is redirected to the advertiser?s website. They clicked to get through to the website which is why it is alleged a click-through. An ad?s bang through amount is bent by how abounding click-throughs the ad receives for every one-hundred impressions that it makes. The allotment of an ad?s click-through amount is usually in the individual digits.
Paying for Banderole Ads
Although there are abounding agency to pay for banderole ads, two of the agency are apparent abundant added than any of the added ways. The a lot of accepted systems acclimated to pay for banderole advertisements are bulleted below.
PPC or Pay Per Click
CPM or Bulk Per Mille
The pay per bang adjustment is about acclimated by publishers who wish to be one-hundred per cent assertive that they do not decay any commercial money. The pay per bang adjustment alone requires the advertiser to pay for their banners if a user clicks on one of the banners and is again directed to the advertiser?s website. A baby fee is paid per anniversary bang that an ad receives. The bulk per mille is usually acclimated by advertisers who wish to advance their name as abundant as accessible and ability accumulation amounts of audiences from all over the web. This adjustment allows them to pay for how abounding times their ad is apparent which gives them the ability to ascendancy the amount of times and bodies that will see their ads. For companies accomplishing accumulation marketing, this adjustment is actual effective.
Different Forms of Banderole Ads
The technology that is acclimated for banderole ads has fabricated cogent developments over the accomplished few years which accept led to the complication and appearance of banderole ads to access drastically. In the aboriginal canicule of banderole ads, argument agreeable banners were just about the alone kinds of banderole ads apparent on the internet. Those ads are now rarely anytime acclimated and apparent on the internet.
Size Expansion ? If a banderole is clicked on it may aggrandize to a abundant beyond admeasurement or if a banderole is formed over by a user with their mouse, the banderole may aggrandize until the user rolls their abrasion off the banner.
Animation ? These are the a lot of accepted forms of banners acclimated today that are loaded with animation. If not created correctly, these banners will be actual ample in admeasurement and will apathetic down the webpage that it is amid on for website visitors.
Menus with Choices ? These banners accept links anchored in them that acquiesce them to aftermath a bead down card with several advertisements on them for users to bang on.
Windows ? Some banderole ads will arise in a abstracted window than the website page if they are loading. This makes them simple to apprehension but they are commonly actual blatant and confusing and not anticipation awful of by internet users.
Rich Media ? Through the use of affluent media such as the technology in Flash, Shockwave and Java, banderole ads can accept videos, acclamation and added alternate appearance that advice them allure users to bang on them.
Checklist for Banderole Designers
Below is a account of tips to advice you if creating your aboriginal banderole ad. These guidelines will advice you actualize the best banderole ad that you can to advice you acquaint for your website.
Make it simple yet appealing. Blatant ads are anon abandoned by a lot of internet users but you aswell wish to accomplish abiding that your ad is noticed.
Do not accomplish it too ample in size. Ads that are ample in computer anamnesis amplitude will accomplish the page yield best to amount and will about-face abroad abounding abeyant ad clickers.
Use abbreviate words and phrases that can be apprehend quick and easily. The faster the user can get your message, the better.
Check to accomplish abiding that your banderole will alloy in on the webpage that it is traveling to be placed on.
Do not use too abundant action so that it is confusing and will yield too continued for the eyewitness to assay and adjudge if they wish to bang on it or not.
Source: http://articlebro.com/2012/arts/movies/air-max-jordan-13-white-black-red/
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Self-driving cars are now street legal in California
Bringing tears to the eyes of gamers everywhere, Nintendo (NTDOY) has confirmed to CVG?that its upcoming Wii U console and its accompanying Wii U GamePad will be region-locked. To bring everybody up to code, Nintendo, along with Sony (SNE) and Microsoft (MSFT) have had a tradition of preventing video game consoles sold in one region from working with video game software from another region. Every home console Nintendo has released since the original Nintendo Entertainment System has been region-locked, as well as its 3DS handheld lineup. The exception to the rule was the DS, which has gone on to sell more than?152 million units worldwide as of July.?The new Wii U console?launches on November 18th?starting at $299.99 for the Basic
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Wednesday, September 26, 2012
Having Problems Brian Urlacher Jersey Winning At Video Games?
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Think about buying used games as an alternative to new online games. Video gaming are often very expensive to get new. Consequently, when you are operating over a limited spending budget, you may want to take into account buying your video gaming used. There are numerous areas where you could acquire second hand online games, which includes auction web sites and native vehicle boot sales.
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In case you are an passionate gamer, visit the mall and search for retailers which promote games which are utilized. This can present you with a sizable discount of occasionally 50-75Per cent of the authentic cost, which can let you get a greater number of games during the duration of the entire year.
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While you have just read through, there are so many methods to enjoy video gaming. When you visit a video video game shop, it may be frustrating to realize how to technique the world of game playing. This information has with a little luck helped you open up your vision to the new guidelines you should use for video games!
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Advantages of having a Mobile Website - Q3 technologies Inc. | Blog ...
Mobile websites are a topic of high interest these days for small and medium businesses. The primary reason for this trend is the popularization of mobile computing in recent years. Mobile internet usage has increased from 6.7% of the total users in Sep 2011 to 12.5% in Sep 2012 which is an increase of 85% in one year. If the same pattern continues, mobile usage could equal desktop usage by the end of 2015.
The main motive of mobile websites is to provide quick information to mobile users who are on the go. These websites are different from full sites in that they contain only the useful information provided in the website in a compact form.
The introduction of tablets and smartphones has been instrumental in the need for creating mobile versions for different websites. Mobile devices provide a simple and a user friendly interface, smooth and fast browsing experience, and the inherent feature of mobility. This makes mobile phones more popular these days and in order to reach out to that large mobile user population, mobile websites are created.
A few features of mobile websites, which make it essential for all websites to develop its own mobile version, are:
- Faster Loading: Mobile websites are designed by keeping the mobile standards in mind. As a website is developed after studying the various parameters of mobile data services, its size is much smaller than its desktop counterpart, allowing users to browse the website with more smoothness and fluidity.
- Offline Media Integration: Offline applications like QR codes can be integrated for mobile websites. Smartphones are provided with the code scanner applications which scans the QR code and redirects the user directly to the website of the product or company. This provides a more flexible marketing technique for different products and companies, specially for start ups, as it wipes out the unnecessary description of a product and simply displays the QR code.
- User Experience: Choosing the content to be added on a mobile website is a bit tricky. Since content is more user-centric, it is important to feature the important content of your website on its mobile version. It should have selected content that the user would be most interested in resulting in higher engagement between a website and its user.
- Cost Effective: Mobile website development is more cost effective as compared to mobile application development in terms of brand awareness and brand identification. Moreover, website development is nearly compatible with all the mobile platforms while there is still usually a need to develop mobile application for each platform separately unless you are performing cross platform mobile application development. This also makes mobile websites more economical than mobile apps.
- Less Development Time: As mobile websites have very basic functionality so it becomes easy for developers to develop mobile websites. The information and content of the mobile website is also limited to it also saves the time of designing and drafting.
- Improves Brand Visibility: Users reaching your mobile website from any source will get the access to the website, be it a mobile device or a tablet or a computer system. This builds a reputation among the users because of the high availability and provides smooth browsing experience to users.
Once a mobile website is ready, proper redirects should be put in place according to the source of the device of a visitor. Whenever a visitor reaches the main website through a mobile device, they should automatically be redirected to the mobile version. Even if a user is redirected from some deeply located desktop version page, arrangements to redirect the user to the same page in mobile version should be made.
Social networking, which is the most popular activity on the internet these days, is getting mobile at a much fasted rate than any other type of online activity.
Tags: mobile compauting, mobile websites, social media, website designing
Source: http://blogs.q3tech.com/2012/09/26/mobile-website-advantages/
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Tuesday, September 25, 2012
Yemen leader says would talk to disarmed al-Qaida
SANAA, Yemen (AP) ? Yemen's president said Tuesday he would talk to his country's branch of the al-Qaida militant network if it were to give up its weapons, abandon its extremist ideas and stop sheltering foreign fighters.
The televised statement by President Abed Rabbo Mansour Hadi appeared aimed at showing his readiness to use any means to reduce the political violence in his country, home to the most world's most active branch of the terror network. Al-Qaida however has shown little indication that it would want to pursue a dialogue, especially under Hadi's conditions.
The militants had taken advantage of Yemen's popular uprising last year to seize much of the country's south. This summer, backed by U.S. advisers and drones, Hadi's military launched an offensive to reclaim this territory, going after al-Qaida's strongholds and hideouts. The groups' No.2 was killed earlier this month in an airstrike.
The militants in turn have struck back, targeted security officials for assassinations and staging deadly bombings.
Hadi's remarks were in line with the image he tries to project, of a leader serious about bringing stability to his country either by force or by negotiation.
He said he was pressured by unidentified local "mediators" to accept the idea of dialogue with the militants. The group has often found shelter among tribal leaders.
"I say, despite the heavy blood that was shed and the homes which were destroyed, and people who lost their homes, a dialogue can be started on condition that the al-Qaida agrees publicly to hand over its weapons, declares its repentance from its extremist ideas that have nothing to do with Islam and gives up sheltering armed groups from outside Yemen," he said. "Then this would be opening the door for dialogue."
He added, however, that "mediators go and never come back," indicating skepticism that al-Qaida would ever take up the offer.
Al-Qaida in the Arabian Peninsula has planned attacks against targets in both Yemen and the United States., including the failed attempt by an al-Qaida operative to detonate a bomb in his underwear aboard a flight bound for Detroit on Christmas Day, 2009.
In May, nearly 100 Yemeni soldiers were killed when a suicide bomber blew himself up at a parade rehearsal. Al-Qaida said at the time it was targeting the defense minister, who was the target of at least six assassination attempts. At least 13 people were killed in the latest attempt against the minister two weeks ago in Sanaa.
Hadi's predecessor Ali Abdullah Saleh was long accused by critics of not fighting al-Qaida wholeheartedly. Saleh stepped down in February in a power transfer deal backed by the U.S., but Hadi and his supporters complain the former leader undermines security using relatives and loyalists still in key positions.
On Tuesday, Hadi vowed to continue to free the country from "burden of the past," an apparent reference to his predecessor's alleged meddling. "All I promise is that I will not be silent or objective before whatever curtails the path to change," he said.
The impoverished Arabian Peninsula nation's economy has been hard hit by the upheaval.
On Tuesday, an explosion struck a gas pipeline in southern Yemen, temporarily halting the flow of gas although exports were not affected, a government official said. The pipeline has repeatedly been targeted by groups suspected to be affiliated with al-Qaida.
An oil ministry official said repair work has begun in the Liquefied Natural Gas Co. pipeline. He spoke on condition of anonymity because he was not authorized to speak to reporters.
The bombing in Shabwa province comes on the heels of a Monday attack against an oil pipeline nearby.
A statement by the gas company said nobody was hurt in Tuesday's explosion. Yemen LNG Co. was created in 1995 ? the country's first natural gas liquefaction consortium. Its major shareholders include French oil company Total SA and Dallas-based Hunt Oil Co. It also is backed with Asian, U.S. and Yemeni government funding.
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Jurors see computer evidence showing search term 'father hates ...
Evidence of?Kaliq Mansor?s Internet history?came before jurors Thursday in the 34-year-old Metzger dad?s?Washington County Circuit Court?murder trial.?
Mansor called 9-1-1 on the afternoon of June 12 last year, reporting that his son, 11-week-old Bryan, wasn?t breathing. Mansor told sheriff?s deputies he went online for advice when the baby struggled to breathe. About 15 minutes passed, he said, before he called 9-1-1.?
Bryan died the following day of abusive head trauma, doctors determined. Mansor is charged with Bryan?s death and the abuse of Bryan?s twin brother, Ethan.?
Detectives served a search warrant at the residence on Sutton Place and seized Mansor?s computers to verify his statement.?
Computer forensics analyst Justin Lazenby testified at trial Thursday about evidence found on the computers.?
Lazenby testified that Internet search terms on the computer included ?11 week old baby pulse no breathing,? ?abuse newborn symptoms,? ?how do I stop abusing my baby? and ?abuser therapy.??
Defense attorney Russell Barnett filed a pre-trial motion to suppress the evidence, arguing that the search of Mansor?s computers was unconstitutional. The motion said the lack of specificity in the search warrant yielded a broad, exploratory search that invaded Mansor?s privacy. Barnett argued police lacked probable cause for delving into so much of Mansor?s personal digital information.?
Judge Don Letourneau denied the motion, and Barnett objected Thursday to Lazenby?s testimony about the contents of Mansor?s Internet history on the basis of relevance.?
The state agreed not to ask Lazenby questions about a game downloaded on the computer called ?Candyvan,? which involves the player abusing children. However, jurors will receive Lazenby?s report, which mentions the game, in evidence.?
According to the report, the game is a ?simple DOS-based program where the protagonist drives around in a van/bus/ice-cream truck, picks up 10 children, and abuses them (physically and/or sexually) while trying to avoid attention and the police.? Certain player actions correspond in the game to words such as, ?You throw the kid to the ground and kick until there?s a pool of blood on the floor.??
Barnett withdrew his objection after prosecutors said they would not question Lazenby about the game.?
Jurors will also see in the report that the computer user accessed information on state child abuse law, ?newborn abuse,? infant injuries, shaken baby syndrome and therapy for abusers, among other related information. The report cites specific searches and web hits, including ?father hates infant? and ?Parents of Newborn Baby Accused of Horrific Abuse.??
Jurors see computer evidence showing search term ?father hates infant? at Metzger dad?s murder trial | OregonLive.com.
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Monday, September 24, 2012
Iran lawmaker accuses IAEA of passing nuclear secrets to Israel
DUBAI (Reuters) - A senior Iranian lawmaker accused the head of the United Nations' nuclear watchdog on Sunday of passing confidential information about Iran's nuclear activities to Israel.
In the latest sign of strained relations with the International Atomic Energy Agency, Javad Jahangirzadeh, a member of parliament's presiding board, said IAEA chief Yukiya Amano would be to blame if Iran reduced its ties with the body.
"Amano's repeated trips to Tel Aviv and asking the Israeli officials' views about Iran's nuclear activities indicates that Iran's nuclear information has been disclosed to the Zionist regime (Israel) and other enemies of the Islamic Republic," Jahangirzadeh was quoted as saying by Iran's English-language Press TV.
"If the agency's actions lead to Iran cutting cooperation with this international body, all responsibility will be with the IAEA director general," said Jahangirzadeh, a member of parliament's national security and foreign policy committee.
The IAEA was not immediately available to comment on his allegation.
Last week, Iranian nuclear energy chief Fereydoun Abbasi-Davani said "terrorists" might have infiltrated the Vienna-based agency. He suggested the IAEA included too much sensitive information about Iran's nuclear program in its reports that he said could be used by saboteurs.
Western diplomats dismissed his allegations as an attempt to distract attention away from the agency's bid to gain access to a site in Iran it suspects was used for nuclear weapons research, something Tehran denies.
Iran blames Israel and its Western allies for the assassination of nuclear scientists in Iran, including an unsuccessful attempt on Abbasi-Davani in November 2010. It also blames those countries for computer viruses that appeared designed to damage its nuclear machinery.
The 35-nation board of the agency censured Iran earlier this month for defying international demands to curb uranium enrichment and failing to address mounting disquiet about its suspected research into atomic bombs.
The resolution prompted Iran's Parliament Speaker, Ali Larijani, to cast doubt on the benefit of Iran's membership in the Nuclear Non-Proliferation Treaty (NPT), the Tehran Times reported.
The commander of Iran's Revolutionary Guards, Mohammad Ali Jafari, told a news conference last week that Tehran would withdraw from the NPT if attacked by Israel which has increased hints it may launch air strikes on Iran's nuclear sites.
Iran's parliament does not decide matters of foreign policy and national security, which are the province of Supreme Leader Ayatollah Ali Khamenei.
(Reporting By Yeganeh Torbati, additional reporting by Fredrik Dahl in Vienna; Editing by Robin Pomeroy)
Source: http://news.yahoo.com/iran-lawmaker-accuses-iaea-passing-nuclear-secrets-israel-112455675.html
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Newark Mayor Booker softens criticism of Obama campaign tactic
Democratic Newark Mayor, and a listed surrogate for Obama's presidential campaign, Cory Booker had some harsh words Sunday on Meet the Press for an Obama campaign ad that seeks to attack Mitt Romney's past as a venture capitalist at Bain Capital.
I?m not about to sit here and indict private equity. To me, it?s just we?re getting to a ridiculous point in America, especially that I know I live in a state where pension funds, unions and other people are investing in companies like Bain Capital. If you look at the totality of Bain Capital?s record, they?ve done a lot to support businesses, to grow businesses.... This kind of stuff is nauseating to me on both sides. It?s nauseating to the American public. Enough is enough. Stop attacking private equity.
Before the day was over, the Romney campaign had released an ad and the GOP had organized an online petition using Booker's words to attack their opponent. As the GOP pounced, Booker backtracked, releasing a video statement in which he reiterated his support for the president and said,
Mitt Romney has made his business record a centerpiece of his campaign. He?s talked about himself as a job creator. And therefore it is reasonable ? and in fact I encourage it ? for the Obama campaign to examine that record and discuss it. I have no problem with that. In fact, I believe that Mitt Romney, in many ways, is not being completely honest with his role and his record even while a businessperson, and is shaping it to serve his political interest ? and not necessarily including all the facts of his time there.
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ScottAukerman: FUN FACT: Without the Sports Chalet theme song, 93% of Americans would not know how to pronounce the word "chalet."
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SEOLinkTagstic: #SEO #VIDEO: Facebook and Standoffs http://t.co/rfaSN74T
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Saturday, September 22, 2012
Beav's brother Tony Dow now an abstract artist
In this Thursday, Sept. 18, 2012 photo, Tony Dow, actor, director and artist, poses with some of his works at his home and studio in the Topanga area of Los Angeles. When it comes time to sitting down in a studio and carving out bronze and wooden sculptures inspired by the nature all around him, Wally isn't leaving it up to the Beav these days. Dow, who famously played the Beaver's older brother Wally on the classic 1950s-60s sitcom "Leave it To Beaver," is carving out a name for himself in the art world these days, as an abstract artist. (AP Photo/Reed Saxon)
In this Thursday, Sept. 18, 2012 photo, Tony Dow, actor, director and artist, poses with some of his works at his home and studio in the Topanga area of Los Angeles. When it comes time to sitting down in a studio and carving out bronze and wooden sculptures inspired by the nature all around him, Wally isn't leaving it up to the Beav these days. Dow, who famously played the Beaver's older brother Wally on the classic 1950s-60s sitcom "Leave it To Beaver," is carving out a name for himself in the art world these days, as an abstract artist. (AP Photo/Reed Saxon)
In this Thursday, Sept. 18, 2012 photo, Tony Dow, actor, director and artist, poses with one of his works at his home and studio in the Topanga area of Los Angeles. When it comes time to sitting down in a studio and carving out bronze and wooden sculptures inspired by the nature all around him, Wally isn't leaving it up to the Beav these days. Dow, who famously played the Beaver's older brother Wally on the classic 1950s-60s sitcom "Leave it To Beaver," is carving out a name for himself in the art world these days, as an abstract artist. (AP Photo/Reed Saxon)
In this Thursday, Sept. 18, 2012 photo, Tony Dow, actor, director and artist, poses with, from left, Adam's Rib, Half Twist and Waiting, at his home and studio in the Topanga area of Los Angeles. When it comes time to sitting down in a studio and carving out bronze and wooden sculptures inspired by the nature all around him, Wally isn't leaving it up to the Beav these days. Dow, who famously played the Beaver's older brother Wally on the classic 1950s-60s sitcom "Leave it To Beaver," is carving out a name for himself in the art world these days, as an abstract artist. (AP Photo/Reed Saxon)
In this Thursday, Sept. 18, 2012 photo, Tony Dow, actor, director and artist, poses with, from left, Two Figures and Struggle, at his home and studio in the Topanga area of Los Angeles. When it comes time to sitting down in a studio and carving out bronze and wooden sculptures inspired by the nature all around him, Wally isn't leaving it up to the Beav these days. Dow, who famously played the Beaver's older brother Wally on the classic 1950s-60s sitcom "Leave it To Beaver," is carving out a name for himself in the art world these days, as an abstract artist. (AP Photo/Reed Saxon)
In this Thursday, Sept. 18, 2012 photo, works by Tony Dow, actor, director and artist, from left, Two Figures and Struggle, are seen at his home and studio in the Topanga area of Los Angeles. When it comes time to sitting down in a studio and carving out bronze and wooden sculptures inspired by the nature all around him, Wally isn't leaving it up to the Beav these days. Dow, who famously played the Beaver's older brother Wally on the classic 1950s-60s sitcom "Leave it To Beaver," is carving out a name for himself in the art world these days, as an abstract artist. (AP Photo/Reed Saxon)
TOPANGA, Calif. (AP) ? He is, and likely forever will be, best known as good old Wally Cleaver, the big brother who had to bail out a goofball sibling facing one dilemma after another on the classic TV series "Leave it to Beaver."
For the last dozen years, though, Tony Dow has been carving out a new career, as a sculptor with pieces that have shown at numerous venues, including what is arguably the world's premier art museum ? the Louvre in Paris.
This weekend, more than 30 of Dow's pieces in bronze, steel and wood go on display closer to home at the Debilzan Gallery in Laguna Beach, and they could fetch several thousand dollars each from collectors. But despite his respected reputation as a sculptor, Dow acknowledges there could be as many people at Saturday's opening reception wanting to rub shoulders with the Beav's brother as see his art.
"I think it's hard, especially with the Wally image, to be taken seriously at pretty much anything other than that," he says with a chuckle and a shake of his head.
At 67, Dow has a head of grey hair and lives with his wife, Lauren, in the wooded Southern California arts colony of Topanga Canyon.
His reputation as a sculptor reached a new height four years ago when he had one of his bronze pieces accepted at 2008's Societe Nationale des Beaux-Arts, a 150-year-old art show staged annually at the Louvre.
The modest, soft-spoken Dow is quick to point out that the work ? a distinctive abstract piece titled The Warrior ? was not placed in the museum's permanent collection. And if you went to see the show that year you would not have found it anywhere near Leonardo da Vinci's "Mona Lisa."
"But it was a show that was represented by 20-some nations, and the U.S. had 14 pieces there, and there were two sculptors, and I was one of them," Dow says between sips of mango-flavored lemonade as he relaxes on a recent hot, end-of-summer day in the living room of his home.
"So it was a big deal," he adds softly with a shy smile.
Dow doesn't complain that he's still associated with his "Leave it to Beaver" character. He loved playing Wally opposite Jerry Mathers' Beaver from 1957 to 1963, so much so that he reprised the role as an adult for a TV movie and 104 more episodes of "The New Leave it To Beaver" during much of the 1980s.
Even now, he still keeps in touch with all the old gang.
"Jerry, I talked to him just a couple days ago," he says of Mathers.
Dressed in a T-shirt, shorts and flip-flops, Dow still looks about as fit as the teenage Wally did. But you probably wouldn't recognize him as that character otherwise ? except for an occasional Wally expression or mannerism.
People who stop him while he walks through his picturesque neighborhood are more likely to ask about his dog Bodie, a dreadlocked Bergamasco Shepherd. It's in the hills of his neighborhood that Dow finds much of the rough-hewn, bark-covered wood known as burl that he carves into intricately detailed sculptures.
Dow is often described as an abstract artist, but a tour of his adjacent home studio shows numerous pieces reflecting a pop art and modern style as well.
The artist himself says he's never paid much attention to labels, although he does cite as major influences the great 19th century French sculptor Auguste Rodin and the modern British abstract artist Henry Moore.
"A lot of people say his work is Rodinish, but it's all Tony," says pop artist Stephano Sutherlin, who has staged several exhibitions of Dow's sculptures at his own gallery in Little Rock, Ark.
"He doesn't copy anybody," Sutherlin said by phone from the gallery. "He likes certain people, but it's his own work, and he's very well respected."
Dow, who painted as a youngster, began sculpting more than 30 years ago when he was still acting and directing. He planned to get serious about it when he retired from television.
"The dream was to get a barn space somewhere at the beach and have a studio," he says. But the beach turned out to be too expensive, and he and his wife instead settled in Topanga in the late 1980s.
It was 12 years ago that art took front and center in his life. Dow laughs when he remembers the day when he decided it was time to take the leap from acting to sculpting. He was up for a role in a TV show and a 28-year-old executive asked, "Have you ever done comedy before," recalls Dow, co-star of one of the most classic TV comedies in history.
"Well, I sort of looked at him and I thought, 'Hmmm, maybe it is time for me to retire. Maybe it is time to take the art seriously.'"
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Sony's Xperia acro S now on sale in unlocked form for $650
Shortly after leaping through the requisite FCC hoops, Sony's 1.5GHz Xperia acro S is now on sale to able and willing Americans. For those who've forgotten, the 4.3-inch smartphone packs a 720p panel, IP55 and IP57 dust / water resistance, inbuilt NFC, Bluetooth, a 12.1-megapixel camera around back, a battery good for up to eight hours of yapping and Android 4.1 (Jelly Bean). In unlocked form, it'll set you back $649.99 -- or, for the Sony faithful, just 64,999 Rewards points. Sadly, you can't get one stamped with a Sony Ericsson logo for the sake of nostalgia at any price. Per usual, the source link is awaiting your order.
[Thanks, Kevin]
Filed under: Cellphones, Mobile
Sony's Xperia acro S now on sale in unlocked form for $650 originally appeared on Engadget on Fri, 21 Sep 2012 17:42:00 EDT. Please see our terms for use of feeds.
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Crew diver drowns on set of new "Lone Ranger" movie
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Source: http://news.yahoo.com/crew-diver-drowns-set-lone-ranger-movie-212945378--finance.html
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